Silane-Based Anti-Microbial

Polymer Additive

HM4100 is polymeric powder that may be compounded into plastics, mixed into coatings, and dispersed in water. The active i BIOSAFE’s technology forms a colorless, odorless, positively charged polymer that creates a molecular bond with the product substrate – making the material itself antimicrobial.

The polymeric antimicrobial powder HM4100 can be dry blended into the bulk resin by any variety of standard mixing operations. The powder will adhere to the surface of the bulk resin particles and become homogeneously mixed. Following mixing the HM4100 into the host resin, it is ready for molding, extrusion, or other thermoplastic processes to make the finished good. Care should be taken to keep this mixture in a dry environment. In certain resins it is recommended that the mixture be dried before it is used. HM4100 is hygroscopic and can hold 5% moisture.

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Resin Compatibility
TPU- Thermoplastic Polyurethane
Urethane Foam
Polyether block amide (PEBAX®)
Polyamide 6 (PA6 or nylon 6)
Silicone (not post-cured)
Acrylic (cast and thermoplastic)
Acrylic Adhesives
Spun Fiber
Fiberglass Gel Coat

Loading Level

Dependent upon the nished goods requirement for e cacy, one can use between 1 part per thousand to 10 parts per thousand of BIOSAFE to base resin by weight (0.1%- 1.0%). BIOSAFE is dispersed throughout the polymer matrix via blending followed by polymer processing (i.e. thermoplastic, thermoset, etc.)


A process temperature of < 170 °C is preferred, but it is time, temperature, and aerobic dependent. BIOSAFE can survive short times at temperatures up to 250 °C if there is little to no oxygen present, as in injection molding or ber spinning.

Time, Oxygen, and Heat History

BIOSAFE is vulnerable to thermal breakdown: A thermal gravimetric analysis shows the product is stable up to about 250 °C in an inert (i.e. Nitrogen) oxygen-free and water-free environment. In commercial use, time, temperature, and chemical reactivity will a ect the stability of BIOSAFE. Additionally the number of heat histories should be minimized. It is preferable to feed the product into an extruder downstream nearest to the die, rather than master batch and go through two full heat histories.

HM4100 Anti-microbial: 84% Dry Powder

EPA Registration Number: 83019-1
CAS# 199111-50-7 (trihydroxy)
Application: Resin blending and compounding

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